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HealthTech Startup Investment Checklist: Series A Stage (2026)

This checklist covers 24 due diligence items for HealthTech startups at the Series A stage. Each item has been validated against institutional investor practice. DDR automates the majority of these checks from a single pitch deck PDF upload.

24 checklist items · 4 red flags automatically detected · See a sample DDR report

Series A Requirements

$1M+ ARR or strong path within 12 months
Proven repeatable go-to-market motion
Net Revenue Retention >100% (expansion > churn)
Gross margins indicating sustainable unit economics
Management team capable of scaling to $10M ARR
Clear competitive differentiation and moat building

HealthTech Sector

FDA regulatory status confirmed (clearance, exempt, or pre-submission in process)
HIPAA compliance program documented with BAA template
Clinical evidence reviewed with methodology assessment
Payor coverage or CPT code strategy documented
Reference customer interviews completed
Data security assessment and breach history reviewed
Stark Law / Anti-Kickback compliance verified for any referral arrangements

Deep Dive

Verify FDA clearance status and any 510(k) submission history
Confirm HIPAA compliance framework: BAA templates, security officer, breach history
Review clinical evidence: study design, sample size, statistical significance
Assess payor coverage and reimbursement status
Interview reference customers (physicians, administrators, patients)

Regulatory

Verify: FDA 510(k) or PMA: medical device and diagnostic claims require pre-market review
Verify: HIPAA: PHI handling requires BAAs, security officer, breach notification protocol
Verify: Stark Law and Anti-Kickback Statute: referral and compensation arrangements in healthcare

OSINT Signals

Check: FDA 510(k) database: verify clearance status and device classification
Check: PubMed: search for published clinical studies mentioning the company
Check: ClinicalTrials.gov: check for registered studies
DDR AUTOMATES THIS CHECKLIST

Upload a HealthTech startup pitch deck and DDR automatically completes 17+ of these 24 checklist items — sourcing data from 13 OSINT signals, benchmarking against 3 comparable companies, and detecting all 4 critical red flags.

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